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MetaDefender™ Email Gateway Security

On-Premises Email Security That Removes Threats Pre-Delivery

MetaDefender Email Gateway Security is OPSWAT's on-premises solution for protecting organizations from phishing, ransomware, and zero-day email threats. It inspects, sanitizes, and controls email content before delivery across enterprise and critical infrastructure environments.

  • Block AI Phishing
  • Sanitize Encrypted Attachments
  • Support Compliance Audits

OPSWAT is Trusted by

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Endpoint Cert. Members

2025 OPSWAT Threat Landscape Report

127%

Increase in Multi-Stage
Malware Complexity*

1 in 14 Files

Initially Deemed ‘Safe’,
Proven to Be Malicious*

7.3%

Of OSINT Files Reclassified
as Malicious Within 24 Hours*

On-Prem Email Security for Phishing, Malware, and Data Loss

MetaDefender Email Gateway Security provides advanced email protection at SMTP/MX level, inspecting inbound and outbound emails before they reach the inbox. It applies real-time anti-phishing, Metascan™ Multiscanning, Deep CDR™ Technology, MetaDefender Aether, Predictive Alin AI, and Proactive DLP™. This combination of technologies helps organizations reduce the window of vulnerability against AI-generated phishing, ransomware, zero-day threats, and sensitive data loss.

Advanced Phishing Detection

Detects phishing attempts, malicious URLs, and socially engineered attacks before delivery

Uses machine learning, sender reputation checks, and on-arrival and time-of-click URL analysis from 30+ online sources to evaluate potentially malicious emails.

Attachment Inspection and Sanitization

Processes email attachments, including encrypted files, and sanitizes them before delivery

Analyzes attachments through successive security layers, applying deeper analysis only when needed so legitimate files move quickly while suspicious files receive additional scrutiny.

Policy Enforcement and DLP

Applies DLP and policy controls across inbound and outbound email workflows

Detects and redacts sensitive data across 125+ file types, including PII, PHI, and credentials, while supporting reporting, audit trails, and compliance evidence.

Key Features & Benefits

Advanced Prevention-First Email Security

Neutralizes threats by applying real-time anti-phishing, Metascan™ Multiscanning, Deep CDR™ Technology, MetaDefender Aether, Predictive Alin AI, and Proactive DLP.

Encrypted Attachment Sanitization

Processes encrypted and password-protected attachments when a password is available or provided, reducing blind spots without creating unnecessary IT workload.

AI Email Threat Detection and Prevention

Uses Predictive Alin AI and MetaDefender Aether to identify unknown, evasive, and file-based threats with rapid verdicts and deeper behavioral analysis when needed.

On-Premises and Air-Gapped Email Security

Supports on-premises, disconnected, and air-gapped environments, helping organizations maintain control, data sovereignty, and resilience.

Pre-Delivery User Exposure Reduction

Inspects and sanitizes every email before delivery, with no noticeable delay for users or disruption to business workflows, which is critical for regulated industries.

See Pre-Delivery Email Protection Policies in Action

Explore how MetaDefender Email Gateway Security inspects incoming and outgoing email content.

Zero-Day Malware Prevention

Effectively eliminate zero-day targeted attacks by relying on prevention rather than detection

Advanced Threat Prevention

Real-time detection of malicious content and unknown threats in attachments

Data Loss Prevention

Ensure compliance with PCI and other regulations for emails, including protection of PII data within companies

Unsolicited Emails

Protect users from social engineering attacks before they reach users, ensuring IT can rely less on user awareness & training

Threat Analysis

Increase the detection rate of unknown threats with unique dynamic analysis technology

Real-Time Anti-Phishing

Reduce accidental threat engagement by uncovering potential phishing attacks at multiple stages before they 
reach users

Attachment Sanitization

Protect business productivity files by removing document-based threats from attachments

  • Zero-Day Malware Prevention

    Effectively eliminate zero-day targeted attacks by relying on prevention rather than detection

  • Advanced Threat Prevention

    Real-time detection of malicious content and unknown threats in attachments

  • Data Loss Prevention

    Ensure compliance with PCI and other regulations for emails, including protection of PII data within companies

  • Unsolicited Emails

    Protect users from social engineering attacks before they reach users, ensuring IT can rely less on user awareness & training

  • Threat Analysis

    Increase the detection rate of unknown threats with unique dynamic analysis technology

  • Real-Time Anti-Phishing

    Reduce accidental threat engagement by uncovering potential phishing attacks at multiple stages before they 
reach users

  • Attachment Sanitization

    Protect business productivity files by removing document-based threats from attachments

MetaDefender™ Email Gateway Security

Real-time Anti-Phishing With a

99.98% Detection Rate

Metascan Multiscanning Through

30+

AV Engines

99.5%

Zero-Day Efficacy Rate Through MetaDefender Aether

Deep CDR™ Technology with 200+ file types supported, including encrypted

<100 ms anti-malware verdict delivery without sandbox detonation

Proactive DLP Covering

125+ File Types

Secure Email Gateway:
Prevention Beyond Detection

MetaDefender Email Gateway Security combines layered inspection, file sanitization, phishing protection, URL analysis, Predictive Alin AI, and policy enforcement to reduce threats before email is delivered and give organizations the utmost tight control on their email flow. Detection-only approaches leave an exposure window, as attackers increasingly use links, trusted file types, and AI-assisted lures
to reach users.

Technology
MetaDefender Email Security
Other Email Security Vendors
Known & Zero-day Malware Protection: Multiscanning
Includes more than 30 anti-malware engines
AI-Generated Malware Detection: Predictive Alin AI 
<100 ms verdict delivery without sandbox detonation
Unknown & Zero-day Exploit Prevention: Deep CDR™ Technology
Supports 200+ file types
Credential Harvesting & Phishing Protection: Real-Time Anti-Phishing
Time-of-click analysis referencing 30+ online sources
Unknown Malware Protection: Real-Time MetaDefender Aether
~10 second fast-pass analysis
Decrypt Password Protected Attachments
Interactive Password Archive decryption

Deployment Options

On-Premises

Deploys in front of existing mail servers at SMTP/MX level or as a second line of defense after existing email gateways.

Disconnected

MetaDefender Email Gateway Security operates without external connectivity, supporting secure email inspection in restricted environments.

Air-Gapped

Supports fully isolated environments requiring local inspection, policy enforcement, and data control.

Integrations

MetaDefender Email Gateway Security integrates with Microsoft Exchange Server, Microsoft 365, Google Workspace, MetaDefender Managed File Transfer, and any SMTP-based email gateway or mail server to inspect inbound and outbound email traffic before delivery. Deployed at the SMTP/MX level, it adds prevention-first protection across existing email ecosystems without requiring organizations to replace their current platforms or disrupt established mail workflows.

Proven Across High-Risk Email
Environments

ABOUT

A major banking institution headquartered in Taipei, with 108 branches in Taiwan, 39 overseas units, and more than 6,000 employees.

USE CASE

The bank needed to reduce malware and phishing risk after conventional email filtering gateways were bypassed. By deploying OPSWAT MetaDefender Email Security with Deep CDR™ Technology and multiscanning, the organization reduced malware attacks entering its network by almost 95%.

ABOUT

Luzerner Psychiatrie AG is a leading provider of psychiatric care across Switzerland, with 20 branches and more than 1,400 employees.

USE CASE

LUPS receives high volumes of emails containing sensitive medical data and needed on-premises protection to meet Swiss data requirements. OPSWAT solutions help secure email attachments, reduce file-based malware exposure, and support compliant data handling.

ABOUT

Hapool Insurance Corporation is a privately owned insurance entity in Israel, supported by all insurance companies within the market and approximately 500 employees.

USE CASE

Hapool Insurance needed to modernize their outdated CDR technology that could not defend against advanced threats such as phishing, malware, and encrypted files. With OPSWAT’s Deep CDR™ Technology, it achieved almost 100% reduction in email threats.

Turn Email Security into Compliance Evidence

MetaDefender Email Gateway Security helps regulated organizations support compliance requirements with prevention-first email security, documented inspection and sanitization outcomes, audit-friendly evidence trails, and DLP across inbound and outbound email workflows. These capabilities are built for the highest security requirements, demonstrate control effectiveness and support timely response expectations across frameworks such as DORA, NIS2, GDPR, and 30 additional frameworks.

FAQs

Microsoft 365 native protection inspects attachments in the cloud using its own detection stack. MetaDefender Email Gateway Security adds Metascan Multiscanning across 30+ AV engines, Deep CDR™ Technology across 200+ file types, and Proactive DLP at the SMTP/MX level on-premises, so attachments are sanitized before delivery rather than scored after it. In Microsoft Exchange Server environments, it runs upstream of Microsoft Defender as a second line of defense.

MetaDefender Email Gateway Security analyzes attachments with Metascan Multiscanning across 30+ AV engines, Deep CDR™ Technology, MetaDefender Aether, and Predictive Alin AI, an AI-powered malware detection engine.

MetaDefender Email Gateway Security analyzes links and attachments before delivery using multiscanning, Deep CDR™ Technology, adaptive sandboxing, and AI-powered malware detection to reduce exposure to file-based ransomware and malicious payloads. Additionally, it does reputation checks, and on-arrival and time-of-click URL analysis from 30+ online sources to evaluate potentially malicious emails.

MetaDefender Email Gateway Security uses real-time anti-phishing, machine learning, reputation checks, and URL analysis to detect sophisticated phishing, including AI-assisted and socially engineered attacks.

MetaDefender Email Gateway Security scans the email body for the password, and automatically inspects, sanitizes and sandboxes the file, before delivering it safely and fully functional if it poses no threat. If no password can be found, the user will receive a notification via email to provide the password through a self-serve portal. Then the file is pushed to Metascan Multiscanning, Deep CDR™ Technology, MetaDefender Aether and Proactive DLP without IT or SOC manual validation.

MetaDefender Email Gateway Security helps enforce email security and data protection policies with DLP, content inspection, redaction, reporting, audit trails, and centralized controls. Compliance readiness covers GDPR, DORA, NIS2 and 30+ additional frameworks. The full list can be accessed on our compliance page.

Yes, MetaDefender Email Gateway Security is built for critical infrastructure, OT, ICS, government, defense, and other regulated environments that need strong control over email-borne risk. MetaDefender Email Gateway Security supports local inspection, data control, DLP, and air-gapped deployment models for environments where cloud-only email security may not meet operational or regulatory requirements.

MetaDefender Email Gateway Security can run upstream of Microsoft Exchange Server or Microsoft Defender in Exchange environments, adding another inspection layer before email reaches users, with no noticeable delays for users or disruption to business workflows.

MetaDefender Email Gateway Security can send security logs to a SIEM-provisioned syslog server using standard syslog and CEF formats, helping organizations centralize monitoring and investigation workflows.

Protect Your Email from Known,
Unknown and Zero-Day Threats

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